About us

About NuGenerex Immuno-Oncology

NuGenerex Immuno-Oncology, Inc. is a platform biotechnology company focused on harnessing the power of the innate immune system to treat cancer and infectious disease with a pipeline of immunotherapy indications based on our proprietary, patented platform technology, Ii-Key.

The Company’s lead immunotherapy product candidate is AE37, an Ii-Key-HER2 peptide vaccine for breast, prostate, and bladder cancer which incorporates our li-peptide linker to a designated antigen that activates the immune system targeting specific cancer cells.

OUR COLLABORATIONS

AE37

• Merck Sharpe & Dohme B.V. (“Merck”) Clinical Trial Collaboration and Supply Agreement for a Phase II clinical trial to evaluate the safety and efficacy of AE37 in combination with the anti-PD-1 therapy, KEYTRUDA (pembrolizumab) in patients with metastatic triple-negative breast cancer. NGIO is sponsoring the clinical trial protocol in collaboration with the National Surgical Adjuvant Breast and Bowel Project (NSABP). (Clinicgov Identifier: NCT04024800)
• Shenzhen Bioscien of China has licensed the rights to the use of AE37 in China for the treatment of prostate cancer.

Ii-Key-SARS-CoV-2 Vaccine

• Bintai Kinden of Malaysia has signed a licensing and distribution agreement to support the development of a COVID-19 vaccine in the U.S in exchange for distribution rights in Southeast Asia.

Ii-Key-SARS-CoV-2, Ii-Key-Swine Flu, Ii-Key-Cancer-Infectious Diseases Vaccines

• Youfeng International Consulting Co., Ltd, & The National Institute for Viral Disease Control and Prevention, Chinese Centre for Disease Control and Prevention (NIVDC) and Beijing Guoxin Haixiang Equity Investment Partnership (collectively referred to as the China Partners) Have set up a joint entity in China to develop and industrialize the Generex internationally patented Ii-Key innovative technology for a Flu peptide vaccine and other vaccines in the People’s Republic of China.

Highlighted joint developments are.

• Ii-Key Vaccine for COVID-19 – Ii-Key-SARS-CoV-2
• Ii-Key Vaccine for Swine Flu – Ii-Key-H1 Swine Influenza Vaccine & Plans to incorporate Ii-Key-H1 vaccine into universal seasonal influenza vaccine
• Ii-Key Platform for Cancer and Infectious Diseases